Extended Data Fig. 4: The most differential KOs between the advanced age (N=116) and offspring (N=232) groups (FDR < 5 × 10-5 and fold change > 2) and their taxonomic contributors.

Fold change is indicated at the top of each scatter plot. The boxes represent the interquartile range (IQR), from the first and third quartiles, and the inside line represents the median. The whiskers denote the lowest and highest values within 1.5 IQR from the first and third quartiles. The circles represent outliers beyond the whiskers.