Extended Data Fig. 7: Tumor incidence analysis on cohorts under long-term FOXM1 transgene induction (related to Fig. 6).
(a) Representative photographs of 88-week-old Rosa26 and FoxM1-dNdK littermates’ necropsy. (b) Post-mortem solid tumor incidence on the indicated cohorts. “n” represents individual mice. (c) Summarization of spontaneous solid tumor formation observed in cohorts indicated in (b). (d) Representative images of liver and kidney histological sections for exclusion of lymphocyte infiltration in n = 3 animals per genotype. Scale bars: 1 cm (a) and 200 μm (d). Error bars represent s.d. Statistics were performed by two-sided Fisher’s exact statistical test for the indicated comparisons.
