On 27 and 28 June 2022, the UK SPINE network (www.kespine.org.uk) held an in-person conference focusing on how new medicines could contribute to improving healthspan (healthy life years). The event facilitated knowledge exchange within the broader geroscience community by bringing together researchers and stakeholders from multiple sectors, including industry, academia, entrepreneurs, small-to-medium-sized enterprises, regulators, patients and carers, investors and policy makers.
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References
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. Cell 153, 1194–1217 (2013).
Guerrero, A. et al. Nature Aging 2, 851–866 (2022).
Guerrero, A. et al. Nat. Metab. 1, 1074–1088 (2019).
Lyles, K. W. et al. N. Engl. J. Med. 357, 1799–1809 (2007).
Sing, C.-W. et al. J. Bone Miner. Res. 33, 1422–1434 (2018).
Wolfe, F. et al. J. Bone Mineral Res. 28, 984–991 (2013).
Pazianas, M., Abrahamsen, B., Eiken, P. A., Eastell, R. & Russell, R. G. G. Osteoporos. Int. 23, 2693–2701 (2012).
Lee, P. et al. J. Clin. Endocrinol. Metab. 101, 1945–1953 (2016).
Sing, C.-W. et al. J. Bone Miner. Res. 35, 1676–1684 (2020).
Woods, T. Healthy longevity for all: a blueprint to maximise equitable health and wealth. colliderhealth.com, https://www.colliderhealth.com/blog/2022/6/29/healthy-longevity-for-all-a-blueprint-to-maximise-equitable-health-and-wealth (28 June 2022).
Woods, T. Live Longer With AI: How Artificial Intelligence Is Helping Us Extend Our Healthspan And Live Better Too (Packt, 2020).
Acknowledgements
We thank all conference participants for sharing their knowledge and insights. Conference speakers and panelists included J. Gil, J. Lord, C. Yelf, P. Bell, C. Jonas, S. Rudkin, E. Platt, L. Fitzpatrick, L. Cox, P. Atherton, S. Miwa, G. Alsaleh, J. Edwards, H. Chance, J. Harris, D. Beaumont-Jewell, Y. Allen, C. Potter, C. Green, A. Leach, E. McDonagh, K. Winn, G. Wilkinson, S. Wilkinson, J. Shorley, A. Steele, T. Woods, M. Bailey, G. Wells, G. Marshall, P. Mercer, C. Cake, M. Ramondt, D. Weinkove, M. Calvert, S. Abbas, E. Marston, M. Hopkins, D. Weinkove, M. Skingle, J. Kiechbusch, M. Ramondt, W. Bains and H. Teare. The authors also thank P. Ovseiko for his input into a draft of this report. The UK SPINE is funded by Research England’s Connecting Capability Fund.
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Crane, P.A., Wilkinson, G. & Teare, H. Healthspan versus lifespan: new medicines to close the gap. Nat Aging 2, 984–988 (2022). https://doi.org/10.1038/s43587-022-00318-5
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DOI: https://doi.org/10.1038/s43587-022-00318-5
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