Extended Data Fig. 5: Gene detection rate in cell-type-specific aging clocks.

a, Unique genes detected in single cell transcriptomes from the subventricular zone as a function of gene detection rate. Red dots indicate unique genes detected at 2%, 20%, and 80% detection rates. b, Upset plots showing transcriptome overlaps between cell types at different levels of expression detection. Most genes are shared if a very low threshold of detection is used. Above 80% detection rate, transcriptomes are very cell type specific. However, the shared core of easily detected genes in transcriptomes (70 genes) is much larger than the shared core of genes selected by clocks (~1).