Extended Data Fig. 6: Differentiation and senescence status of spike-specific CD4+ T cells. | Nature Aging

Extended Data Fig. 6: Differentiation and senescence status of spike-specific CD4+ T cells.

From: Impaired CD4+ T cell response in older adults is associated with reduced immunogenicity and reactogenicity of mRNA COVID-19 vaccination

Extended Data Fig. 6

(a) Frequency of NaĆÆve, Tscm, CM, EM, and TEMRA in AIM+ CD4+ T cells. (b) Frequency of CD28+ and CD57āˆ’ in AIM+ CD4+ T cells. The centerline and error bars indicate the median and interquartile range (IQR). Statistical comparisons across cohorts were performed using the Mann-Whitney test. ns, not significant. Blue and red dots represent adults (nā€‰=ā€‰107) and older adults (nā€‰=ā€‰109), respectively.

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