Table 1 Characteristics of CALERIE Trial participants at baseline

From: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

 

AL

CR

N/mean

(%/s.d.)

N/mean

(%/s.d.)

CALERIE participant characteristics at baseline

Age at baseline (yr)

38

(7)

38

(7)

Energy intake (kcal d−1)

2,045

(481)

2,124

(558)

Sex

    

 Women

53

(71%)

100

(69%)

 Men

22

(29%)

45

(31%)

Race/ethnic identity

 White

57

(76%)

111

(77%)

 Black

11

(15%)

16

(11%)

 Other

7

(9%)

18

(12%)

Study site

    

 A

25

(33%)

47

(32%)

 B

27

(36%)

53

(37%)

 C

23

(31%)

45

(31%)

BMI stratum

 22.0–24.9 kg m−2

37

(54%)

70

(48%)

 25.0–27.9 kg m−2

38

(55%)

75

(52%)

Analysis sample characteristics at baseline

Age at baseline

38

(7)

38

(7)

Energy intake (kcal d−1)

2,023

(469)

2,130

(540)

Sex

    

 Women

48.00

(70%)

89

(70%)

 Men

21.00

(30%)

39

(30%)

Race/ethnic identity

    

 White

52.00

(75%)

100

(78%)

 Black

10

(14%)

13

(10%)

 Other

7

(10%)

15

(12%)

Study site

    

 A

24

(35%)

42

(33%)

 B

25

(36%)

45

(35%)

 C

20

(29%)

41

(32%)

BMI stratum

    

 22.0–24.9 kg m−2

33

(48%)

60

(47%)

 25.0–27.9 kg m−2

36

(52%)

68

(53%)

  1. The table shows data for participants randomized to the AL control group and the CR treatment group. CALERIE included a total of N = 220 participants (AL n = 75, of whom n = 71 completed the study; CR n = 145, of whom n = 118 completed the study). The analysis sample was composed of CALERIE participants for whom DNAm data were available at baseline and at least one follow-up assessment (‘analysis sample’; N = 197; AL n = 69, CR n = 128).