Extended Data Fig. 3: Universal clocks applied to species with fewer than 15 samples. | Nature Aging

Extended Data Fig. 3: Universal clocks applied to species with fewer than 15 samples.

From: Universal DNA methylation age across mammalian tissues

Extended Data Fig. 3: Universal clocks applied to species with fewer than 15 samples.The alternative text for this image may have been generated using AI.

The title of each panel lists the type of universal clock: a, Clock 1 = basic universal clock based on log(Age + 2), b, d, Clock 2 = universal clock for relative age, c, Clock 3 =universal clock for log-linear age. Leave-one-fraction-out (LOFO) methylation estimates versus a–c, chronological age or d, relative age for clock 2. The respective inverse transformations were applied to arrive at DNA methylation-based estimates of chronological age in years or relative age (y-axis).

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