Fig. 5: Methylation levels of cg12841266 (LHFPL4) versus chronological age in mouse tissues.
From: Universal DNA methylation age across mammalian tissues
Results are reported for different tissues and age groups. a–g, Postnatal development (dev.) (from 1 week to 6 weeks). h–o, Age effects in adult mice. Mean ± s.d.96 of chronological age is 3.5 ± 1.7 (1.0–6.0) weeks in the developmental age group and 1.12 ± 0.72 (0.15–2.78) years in the post-developmental group. a,h, All tissues combined. Each dot (sample) is colored by the tissue type. o, Pearson correlations between the CpG site and age in additional mouse tissues and cell types from the Mammalian Methylation Consortium. Hemato.prog.LSK, hematopoietic progenitor cells with lineage−Sca-1+c-Kit+ phenotype; max, maximum; min, minimum; n, sample size; SVZ, subventricular zone. Pearson correlation coefficients and nominal (unadjusted) two-sided correlation test P values are shown.
