Extended Data Fig. 1: Old HSCs have higher mitochondria content.

Mitochondrial DNA (mtDNA) quantification by QPCR expressed as fold change compared to young HSCs. Young values are normalized on their mean value (P-value = 0.0571) (n = 4; values are mean ± s.e.m.; two-tailed Mann-Whitney test; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001).