Extended Data Fig. 2: Chromatin modifications in the microglial aging process.
From: Transcriptional and epigenetic decoding of the microglial aging process
(a) Percentages of differential chromatin accessibility in gene coding and regulatory elements at 3 ages. (b) Chromatin accessibility of ADEM genes at each age. Standardized values were calculated according to peak counts of the promoter region. (c-d) Encoding counts of genes encoding ADEM-enriched transcription factors at each age. Data are presented as mean ± SD. N = 2 ATAC-seq tests for each group. Microglia from 2 to 3 mice were pooled together for each ATAC-seq test. MO: month-old; ADEM: age-dependent microglia.
