Extended Data Fig. 6: Each microglial cell proliferates several times by 3xDR.
From: Transcriptional and epigenetic decoding of the microglial aging process
(a) Scheme of the forced microglial turnover model and timepoints for experiments. (b) Representative spatial distribution of microglia in 3 rounds of depletion-repopulation. Each green dot represents an IBA1+ microglial cell. (c) Statistics of IBA1+ cell number in each round of microglial depletion-repopulation. Data are represented as the mean ± SD. N = 6 (1xDPL, 2xDPL, 3xDPL, 1xDR and 2xDR) to 7 mice (3xDR) for each group. PLX5622: PLX5622-formulated diet; CD: control diet; NxDPL: N-round depletion; NxDR: N-round depletion-repopulation.
