Extended Data Fig. 10: 3xDR does not influence the adult neurogenesis, neuron number or OPC density.
From: Transcriptional and epigenetic decoding of the microglial aging process
(a) Quantification of Ki67+ DCX+ cell numbers in microglia in the dentate gyrus. 3xDR does not influence adult neurogenesis in the dentate gyrus. N = 7 and 6 mice for control and 3xDR, respectively. (b) NeuN quantification in CA1. 3xDR does not influence the NeuN thickness of CA1. N = 8 and 7 mice for control and 3xDR, respectively. (c) 3xDR does not influence the OPC density. N = 8 and 7 mice for control and 3xDR, respectively. Data are presented as mean ± SD. Two-tailed independent t test. Ctrl: control; 3xDR: 3-round depletion-repopulation.
