Extended Data Fig. 5: VCAM1+ microglia interact with amyloid-beta plaques in the brains of patients with Alzheimer’s disease.
From: The VCAM1–ApoE pathway directs microglial chemotaxis and alleviates Alzheimer’s disease pathology
a,b, Representative images (a) and bar plot (b) showing the proportions of amyloid-beta (Aβ) plaque-associated VCAM1+ microglia in postmortem Alzheimer’s disease brain sections (n = 5 patients with Alzheimer’s disease; two-way ANOVA with Šidák’s multiple comparisons test). Arrowheads indicate the VCAM1+ microglia associated with plaque. Scale bar = 10 μm. All data are mean ± s.e.m.
