Extended Data Fig. 3: Adjusted mean change in tau PET SUVR from baseline to week 78.

Adjusted mean change from baseline (±SE) in tau PET SUVR in brain regions corresponding to (a) medial temporal cortex, (b) lateral temporal cortex, and (c) frontal cortex. Sample sizes are provided for each group at each time point and are the same for all panels. Analyses were two-sided at 5% significance level. No adjustments were made for multiple comparisons.