Extended Data Fig. 5: Batch correction of TMT experiments. | Nature Aging

Extended Data Fig. 5: Batch correction of TMT experiments.

From: Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles

Extended Data Fig. 5: Batch correction of TMT experiments.

a) Biplot of first two principal components on unnormalized protein abundances have batch effects between TMT experiments as indicated by the non-overlapping circles that correspond to all 44 TMT experiments. b) Batch effects were successfully removed with the Internal Reference Scaling method as described in the online methods.

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