Extended Data Fig. 7: Working model.
From: Age-related noncanonical TRMT6–TRMT61A signaling impairs hematopoietic stem cells
(a) This chart illustrates the proposed model of TRMT6/61A→3’-tiRNA-Leu-CAG →RIPK1→RIPK3→MLKL cascade promotes hematopoietic stem cell aging. (b) This chart illustrates the summary model of the connection between molecular mechanisms and cellular phenotypes.
