Extended Data Fig. 7: Genetic correlations using sex-stratified GWAS results.
From: The genetic architecture of biological age in nine human organ systems
The genetic correlation between each pair of BAGs was determined using sex-stratified GWAS summary statistics from our analyses. Most of the genetic correlations showed consistency between females and males, albeit sex differences are evident in certain BAGs, particularly in the cardiovascular BAG results. Specifically, males exhibit dominant correlations between cardiovascular BAGs and hepatic and renal BAGs, while females demonstrate specific correlations with musculoskeletal and pulmonary BAGs. All P-values were two-sided, and Bonferroni correction was employed to denote significant signals (* symbols).
