Extended Data Fig. 3: Trumpet plots of the alternative allele frequency vs. the beta coefficient of the nine BAG GWASs.
From: The genetic architecture of biological age in nine human organ systems
The trumpet plots display the inverse relationship between the alternative (effect) allele frequency and the effect size (beta coefficient) for the brain, cardiovascular, eye, hepatic, immune, metabolic, musculoskeletal, pulmonary, and renal BAGs. Only the independent significant SNPs were considered. The dot size corresponds to the effect size, while the transparency of the dot is proportional to its statistical significance.
