Extended Data Fig. 4: Morphometry of mouse oocytes in primordial and antral follicles at multiple ages. | Nature Aging

Extended Data Fig. 4: Morphometry of mouse oocytes in primordial and antral follicles at multiple ages.

From: Maternal age enhances purifying selection on pathogenic mutations in complex I genes of mammalian mtDNA

Extended Data Fig. 4

(a) Morphometric analysis of oocytes and surrounding somatic cells in primordial follicles from female mice at various developmental stages (P3, P7, P21, 8 weeks, 14 weeks, 22 weeks, and 32 weeks), and oocytes in antral follicles from P21 females. The diameters of oocytes (red) and somatic cells (soma) were measured. Oocytes are indicated in red, granulosa cells in black and red blood cells in purple. (b) The violin plots show the distribution of diameters for oocytes (n = 382 from 2 females) from primordial follicles in P3 mice, and granulosa cells (n = 314 from 2 females), delineating the variability in size of both cell types.

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