Extended Data Fig. 4: p21high and p16high cells are distinct. | Nature Aging

Extended Data Fig. 4: p21high and p16high cells are distinct.

From: Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing

Extended Data Fig. 4

(a) UMAP plots showing tdTomato expression levels. (b) UMAP plots showing p16 expression levels. (c) Bubble plots displaying gene enrichment in p21+ cells versus p21- cells in wounded PT samples across 4 cell types. Genes with an adjusted p value less than 0.05 are shown. (d) Bubble plots displaying gene enrichment in p16+ cells versus p16- cells in wounded PT samples across 4 cell types. Two-side MAST test was used for c and d. Multiple comparisons were adjusted using False Discovery Rate (FDR) correction. Genes with an adjusted p value less than 0.05 are shown.

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