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Torpor

Cold is hot for slowing aging

Nature Aging volume 5, pages 344–345 (2025)Cite this article

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Hrvatin and colleagues explore the antiaging mechanisms of torpor, and separate the roles of metabolic rate and body temperature. The study demonstrates that hypothermia, and not hypometabolism, drives deceleration of epigenetic aging, which positions body temperature as a pivotal target in aging research.

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Fig. 1: Hypothermia and aging.

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Authors and Affiliations

  1. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

    Matteo Cerri

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  1. Matteo Cerri
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Correspondence to Matteo Cerri.

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The author declares no competing interests.

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Cerri, M. Cold is hot for slowing aging. Nat Aging 5, 344–345 (2025). https://doi.org/10.1038/s43587-025-00817-1

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