Extended Data Fig. 1: ACE expression in microglia from wildtype, 5xFAD and ACE10/10 mice. | Nature Aging

Extended Data Fig. 1: ACE expression in microglia from wildtype, 5xFAD and ACE10/10 mice.

From: Boosting angiotensin-converting enzyme (ACE) in microglia protects against Alzheimer’s disease in 5xFAD mice

Extended Data Fig. 1

Representative immunofluorescence images from 6-month-old brain cut in the coronal plane at -2mm Bregma from wildtype (WT), homozygous 5xFAD (5xFADTg/Tg) and homozygous ACE10/10 mice using antibodies to Iba1 to label microglia (green) and ACE (magenta). Representative images depicted were derived from analysis of n = 3 mice of each genotype and 2 brain sections per mouse with consistent results. (scale, 100 µm).

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