Fig. 4: Proteomics integration in the UK Biobank. | Nature Aging

Fig. 4: Proteomics integration in the UK Biobank.

From: Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty

Fig. 4: Proteomics integration in the UK Biobank.The alternative text for this image may have been generated using AI.

a,b, Protein associations (beta coefficients) with the full HFRS (a) and HFRS without dementia (b) the in the UK Biobank using linear regression models (N = 34,879–42,495; exact N for each model is given in Supplementary Table 10). All models were adjusted for birth year, sex and the first ten PCs (model 1), and additionally adjusted for batch, baseline assessment center, BMI and smoking (model 2). Solid dots indicate statistically significant associations at an FDR < 0.05. The bars indicate 95% confidence intervals.

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