Fig. 5: HFRS-PRSs, frailty, mortality, and hospitalizations. | Nature Aging

Fig. 5: HFRS-PRSs, frailty, mortality, and hospitalizations.

From: Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty

Fig. 5: HFRS-PRSs, frailty, mortality, and hospitalizations.The alternative text for this image may have been generated using AI.

a–d, Associations of the HFRS-PRSs with the HFRS (a), early-onset frailty (b), all-cause mortality (c) and number of hospitalizations (d) in the UK Biobank (N = 407,463). All models included birth year, birth region, sex and the first ten PCs as covariates. The bars indicate 95% confidence intervals of the beta coefficients, odds ratios (ORs) and hazard ratios (HRs).

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