Extended Data Fig. 3: Changes in abundance of epithelial, stromal, and immune cell populations with age in ER+ breast cancer. | Nature Aging

Extended Data Fig. 3: Changes in abundance of epithelial, stromal, and immune cell populations with age in ER+ breast cancer.

From: Cell populations in human breast cancers are molecularly and biologically distinct with age

Extended Data Fig. 3: Changes in abundance of epithelial, stromal, and immune cell populations with age in ER+ breast cancer.

a, Stacked bar charts representing the indicated minor cell populations as a proportion of respective major cell populations in ER+ breast tumors from the human breast cancer atlas23. Samples are ordered along x axes by donor age, from youngest to oldest; samples that did not have any cells of a given major cell type are excluded from the plots. b, Scatter plots representing Pearson correlation between donor age and cell proportion (from a) for each of 28 cell subpopulations Plots depict the line of best fit and 95% confidence interval following Pearson correlation analysis. p.adj indicates Benjamini-Hochberg-adjusted two-sided Pearson’s correlation coefficients.

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