Extended Data Fig. 10: Intestinal immune microenvironment analysis after YNP treatment.
a, Violin plot of genes identified for immune cell in the intestine. b, c, t-SNE map for regrouping analysis of immune cells and corresponding quantitative results. d-f, Highlight t-SNE map of representative genes in DCs. g, h, Representative plots for the gating strategy of DC subset and corresponding quantitative results (n = 5, biological replicates per group). P values (from left to right): **P = 0.0034, **P = 0.0092, *P = 0.0126, *P = 0.0482. i, Dotplot of representative gene Itgae expression in DC subsets. j, Representative migration and endocytosis related genes in DCs subset. k, KEGG enrichment analysis of upregulated genes in CD103+ cDC2. Data are means ± SEM. Statistical analysis was performed using Student’s t-test (two-tailed). NS, not significant.
