Extended Data Fig. 9: Compartment Enriched Genes Are Affected by Age. | Nature Aging

Extended Data Fig. 9: Compartment Enriched Genes Are Affected by Age.

From: Simultaneous spatial transcriptomics and morphology profiling as tools to explore how microglia change with age

Extended Data Fig. 9: Compartment Enriched Genes Are Affected by Age.The alternative text for this image may have been generated using AI.

A, Heatmap showing genes cluster by location of transcripts in young mice. B, Heatmap showing genes cluster by location of transcripts in aged mice. C, Average correlation between process enriched genes with different morphological characteristics at each age, colored by age of mouse. D, Classifier performance as quantified by receiver operator characteristic curve (ROC) for samples from young or old mice. E, Importance of individual genes in each age stratified classifier as calculated through mean decrease in impurity.

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