Extended Data Fig. 1: Spatial Transcriptomics Resolves Cell Types Across the Aging Mouse Brain. | Nature Aging

Extended Data Fig. 1: Spatial Transcriptomics Resolves Cell Types Across the Aging Mouse Brain.

From: Simultaneous spatial transcriptomics and morphology profiling as tools to explore how microglia change with age

Extended Data Fig. 1: Spatial Transcriptomics Resolves Cell Types Across the Aging Mouse Brain.The alternative text for this image may have been generated using AI.

A, Number of cells passing minimum number of transcripts per cell threshold (red line) (left) with a representative spatial heatmap in a young (middle) and old (right) brain. B, Number of cells passing minimum number of genes threshold (red line) (left) with a representative spatial heatmap in a young (middle) and old (right) brain. C, UMAP representation of the spatial transcriptome of all cells passing QC (n = 991,315), colored by major cell class. D, UMAP representation of all cells passing QC, colored by brain region. E, UMAP representation of all cells passing QC, colored by age. The violin plots are demarcated with median values and lines representing the first and third quartiles.

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