Table 4 Comparison of within-subject dissimilarities between infants with CF with higher number of RTIs and lower number of RTIs

From: Early nasal microbiota and subsequent respiratory tract infections in infants with cystic fibrosis

Antibiotic treatment

RTI

Higher number of RTIs N; consecutive swabs

Lower number of RTIs N; consecutive swabs

Estimate (higher number)a

95% CIa

P valuea

All

All

15; 243

35; 464

−0.064

−0.100, −0.027

0.00071

Before

All

13; 115

29; 282

−0.068

−0.136, −0.026

0.00020

All

Before

14; 59

33; 276

−0.069

−0.133, −0.005

0.038

  1. RTI respiratory tract infection, CI confidence interval, All all samples were included irrespective of antibiotic treatment or RTI, Before only samples before the first antibiotic treatment or RTI were included.
  2. aGamm model corrected for breastfeeding, siblings, mode of delivery, antibiotic therapy, season (fixed effects), sweat chloride, age in weeks (smooth term) and subject (random effect).
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