Table 5 Comparison of α-diversity between infants with CF with higher and lower number of RTIs

From: Early nasal microbiota and subsequent respiratory tract infections in infants with cystic fibrosis

Antibiotic treatment

RTI

Mean SDI RTI lower/higher number

Estimatea (Higher number of RTIs)

95% CIa

P valuea

All

All

2.260/1.838

−0.395

−0.589, −0.201

0.000068

Before

All

2.128/1.564

−0.528

−0.805, −0.251

0.00022

All

Before

2.157/1.625

−0.464

−0.826, −0.103

0.014

  1. RTI respiratory tract infection, SDI Shannon-Diversity Index, CI confidence interval, All all samples were included irrespective of antibiotic treatment or RTI, Before only samples before the first antibiotic treatment or RTI were included.
  2. aGamm model corrected for breastfeeding, siblings, mode of delivery, antibiotic treatment, season (fixed effects), sweat chloride, age in weeks (smooth term), and subject (random effect).
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