Fig. 9: Correlation between regional excitation-inhibition (E-I) balance and cognitive measurement.

Scatter plots between total E-I difference and Mini-Mental State Examination (MMSE) score for a Left insula (L.IN), b Left putamen (L.PUT), c right putamen (R.PUT), and d Left hippocampus (L.HPC). Scatter plots between total E-I difference and Clinical Dementia Rating (CDR) score for e Right posterior cingulate cortex (R.PCC), f Right putamen (R.PUT), g Right pallidum (R.PAL), and h Left hippocampus (L.HPC). The Pearson’s correlation coefficient (r) and the associated corrected p value are displayed for each region. One star (*) indicates corrected significance by FDR (p < 0.05), and double stars (**) denote corrected significance by the Bonferroni method (p < 0.05).