Table 2 Multivariable analysis of kidney transplantation events in the 71,583 CDR during the pre-pandemic and pandemic periods (cause-specific Cox models)

From: Evolving impact of the COVID-19 pandemic in chronic dialysis recipients in France

Model

Variable

Kidney transplantations (n) / person-years (n)

HR [95% CI]

p value

Model 1

Pre-pandemic period

5853/98,444

1 (reference)

 
 

Pandemic period

4172/86,465

0.72 [0.70–0.76]

<0.01

Model 2

Pre-pandemic period

5853/98,444

  
 

Pandemic period, no history of COVID-19-related hospitalization (vs. pre-pandemic period)

4060/82,804

0.73 [0.70–0.76]

<0.01

 

Pandemic period, ≥1 COVID-19-related hospitalization (vs. pandemic period, no hospitalization)

112/3661

0.71 [0.59–0.85]

<0.01

Model 3

Pre-pandemic period

5853/98,444

1 (reference)

 
 

1st wave

67/6837

0.16 [0.12–0.20]

<0.01

 

1st inter-wave

505/9892

0.80 [0.73–0.88]

<0.01

 

2nd wave

1024/21,604

0.73 [0.69–0.79]

<0.01

 

2nd inter-wave

874/17,503

0.77 [0.71–0.82]

<0.01

 

3rd wave

673/13,075

0.76 [0.70–0.82]

<0.01

 

3rd inter-wave

1029/17,553

0.81 [0.76–0.87]

<0.01

  1. All HR shown correspond to cause-specific Cox regressions also adjusted for the following covariates: sex, age category, diabetes, and cardiovascular disease.
  2. CI confidence interval, CDR chronic dialysis recipients, HR hazard ratio.