Table 4 Multivariable analysis of COVID-19-related hospitalization after a given number of vaccine doses received in the CDR and matched controls (cause-specific Cox model)

From: Evolving impact of the COVID-19 pandemic in chronic dialysis recipients in France

Number of vaccine doses

CDR

  

Matched controls

  
 

Individuals with a COVID-19 hospitalization (n)/person-years (n)

HR [95% CI]

p value

Individuals with a COVID-19 hospitalization (n)/person-years (n)

HR [95% CI]

p value

0 or 1

3006/39,494

  

2397 / 116,699

  

2 (vs. 0 or 1)

351/12,149

0.37 [0.32–0.42]

<0.01

264 / 42,935

0.28 [0.24–0.32]

<0.01

3 (1st booster, vs. 2)

618/19,430

0.66 [0.56–0.77]

<0.01

486 / 49,045

0.60 [0.51–0.72]

<0.01

4 (2nd booster, vs. 3)

396/6915

0.83 [0.72–0.94]

<0.01

113 / 8554

0.77 [0.62–0.98]

0.03

  1. All HR shown correspond to cause-specific Cox regressions also adjusted for the following covariates: sex, age category, diabetes, cardiovascular disease, and wave and inter-wave sub-periods; they are reported per additional vaccine dose (i.e. 2 vs. 0 or 1, 3 vs. 2, and 4 vs. 3, respectively).
  2. CI confidence interval, CDR chronic dialysis recipients, HR hazard ratio.
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