Table 2 Sub-clinical characteristics of pneumoniae in children before treatment

From: Nasal-spraying Bacillus spore probiotics for pneumonia in children with respiratory syncytial virus and bacterial co-infections: a randomized clinical trial

Characteristic

Control group (N = 50)

Navax group (N = 51)

p value

Total. n (%)

Min - max

Total. n (%)

Min - max

 

Chest X-ray

     

Normal

1 (2.00)

 

1 (1.96)

 

0.9639a

Ground-glass opacity nodules in both lung fields

39 (78.00)

 

37 (72.55)

 

Bronchial wall thickening

2 (4.00)

 

3 (5.88)

 

Upper lobe opacities P

3 (6.00)

 

3 (5.88)

 

Osler's nodes, interstitial injury, hyperinflation

5 (10.00)

 

7 (13.73)

 

RSV Positive

     

Rapid test

50 (100)

 

51 (100)

 

>0.9999a

Real-time PCR

50 (100)

 

51 (100)

 

>0.9999a

Hematology and Biochemistry

Total white blood cells (G/L) -b

 

4.99–26.96

 

5.69–25.50

 

Below standard range

0 (0.00)

 

0 (0.00)

 

-c

Within standard range

45 (90.00)

 

42 (82.35)

 

0.2661b

Above standard range

5 (10.00)

 

9 (17.65)

 

Neutrophil (G/L) -c

 

0.9–19.36

 

1.36–22.80

 

Below standard range

1 (2.00)

 

0 (0.00)

 

0.423a

Within standard range

35 (70.00)

 

40 (78.43)

 

Above standard range

14 (28.00)

 

11 (21.57)

 

Hemoglobin (g/dL) (Children ≥ 6 months)

89–125

 

86–138

 

<110

8 (16.00)

 

5 (9.80)

 

0.4255b

≥110

15 (30.00)

 

16 (31.37)

 

Total platelet count (G/L)

     

<150

0 (0.00)

 

0 (0.00)

 

-c

150 - 450

34 (68.00)

 

32 (62.75)

 

0.579b

>450

16 (32.00)

 

19 (37.25)

 

CRP (mg/L)

     

>40

36 (72.00)

 

43 (84.31)

 

0.1339b

≤40

14 (28.00)

 

8 (15.69)

 

Bacterial co-infection detected by real-time PCR

    

H. influenzae (HI)

33 (66.00)

 

25 (49.02)

 

0.1258a

S. pneumoniae (SP)

5 (10.00)

 

11 (21.57)

 

M. pneumoniae (MP)

2 (4.00)

 

1 (1.96)

 

B. pertussis (BP)

0 (0.00)

 

1 (1.96)

 

H. influenzae + S. pneumoniae

7 (14.00)

 

13 (25.49)

 

H. influenzae + B. pertussis

1 (2.00)

 

0 (0.00)

 

S. pneumoniae + M. pneumoniae

1 (2.00)

 

0 (0.00)

 

H. influenzae + S. pneumoniae + M. pneumoniae

1 (2.00)

 

0 (0.00)

 
  1. Bold and Italic text represents subgroup means.
  2. aChi-Square test.
  3. bFisher’s Exact test.
  4. cThere is no remaining patients to compare the significance.
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