Table 1 Descriptive statistics for the TCGA cohort according to recurrence outcome and tumor grade

From: A deep learning model to predict glioma recurrence using integrated genomic and clinical data

 

Late glioma recurrence (TTR ≥ 390 days)

Early glioma recurrence (TTR < 390 days)

 

Tumor grade (n)

All (109)

II (52)

III (52)

IV (5)

All (82)

II (21)

III (36)

IV (25)

Sex [n]

Male

58

28

28

2

49

10

22

17

Female

51

24

24

3

33

11

14

8

Race [n]a

White

102

48

49

5

74

18

35

21

African American or Black

5

2

3

0

5

2

1

2

American Indian or Alaska Native

1

1

0

0

0

0

0

0

Asian

0

0

0

0

2

1

0

1

Hispanic or Latino [n]a

No

95

40

50

5

77

20

35

22

Yes

4

4

0

0

1

0

1

0

Histology [n]b

Astrocytoma

57

35

22

0

24

13

11

0

Glioblastoma

24

3

16

5

42

4

13

25

Oligodendroglioma

24

14

10

0

9

2

7

0

Astrocytoma wildtype

4

0

4

0

7

2

5

0

IDH & 1p19q codeletion status [n]

IDH-mutant, non-codeleted

57

35

22

0

24

13

11

0

IDH-wildtype

28

3

20

5

49

6

18

25

IDH-mutant, codeleted

24

14

10

0

9

2

7

0

Vital status [n]

Deceased

56

18

34

4

56

9

25

22

Alive

53

34

18

1

26

12

11

3

Days to recurrence

Median

809.0

869.0

690.5

566.0

202.5

265.0

196.5

176.0

IQR

698.0

664.5

694.3

293.0

164.0

160.0

166.5

161.0

Age [yr]

Median

41.0

35.0

45.0

63.0

52.5

41.0

52.5

57.0

IQR

19.0

11.0

20.3

1.0

19.0

23.0

20.0

10.0

  1. Bracketed numbers next to tumor grade indicate the number of included patients.
  2. aRace and ethnicity were unavailable for 2 and 14 patients, respectively.
  3. bHistology represents the reassigned labels, as described in Methods and Fig. 2.