Fig. 2: Differential abundance analysis of peptides and proteins in matched cerebrospinal fluid (CSF) and plasma of young (n = 52) and older (n = 40) adults. | Communications Medicine

Fig. 2: Differential abundance analysis of peptides and proteins in matched cerebrospinal fluid (CSF) and plasma of young (n = 52) and older (n = 40) adults.

From: Unveiling proteomic and peptide-level modifications in cerebrospinal fluid and plasma in normal cognitive aging

Fig. 2

a Volcano plot showing proteins differentially expressed in plasma with age; b Venn diagram illustrating the overlap of differentially expressed proteins between plasma and CSF; c Volcano plot showing proteins differentially expressed in CSF with age; d Volcano plot showing peptides differentially expressed in plasma with age; e Volcano plot showing peptides differentially expressed in CSF with age. Proteins and peptides highlighted in the volcano plots meet the criteria of p value <0.05 and log2 fold change (LogFC) <–0.58 or >0.58. The source data for Fig. 2 is in Supplementary Data s1–s4. (Created with BioRender.com).

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