Table 1 Participants in Hyperacusis (HA) and Control (CTR) groups: demographics, Pure-tone audiometry (PTA), Loudness discomfort levels (LDL), Hyperacusis Questionnaire17 score (HQ), and clinician’s ratings for depressive symptoms (MDD) based on Structural Clinical Interview for DSM-520

From: Sparse machine learning of resting-state fMRI reveals brain-wide dysconnectivity in hyperacusis

 

Hyperacusis (HA)

Controls (CTR)

p-value, Hedges’ g [95% CI]

No. of participants

14

25

-

Age (years)

19 ± 2

20 ± 2

n.s (= 0.5279) #

Sex

9 F, 5 M

13 F, 12 M

n.s (= 0.5178) ^

PTA average

0.5,1,2,4 kHz (dB HL)

7.01 ± 2.67

8.33 ± 2.84

n.s (= 0.1725) #

g = -0.45 [-1.13, 0.2]

LDL 1 kHz (dB HL)

85.71 ± 10.2

94.4 ± 8.19

=0.0148 #

g = -0.92 [-1.52 -0.32]

LDL 4 kHz (dB HL)

80.18 ± 11.59

88.7 ± 12.69

=0.0481 #

g = -0.66 [-1.34 -0.04]

LDL speech (dB HL)

84.64 ± 9.11

93.3 ± 8.08

=0.0084 #

g = -0.98 [-1.76 -0.23]

HQ score (0–42)

26.07 ± 2.84

8.8 ± 4.37

=1.4e-16 #

g = 4.23 [3.1 5.62]

MDD ratings (absent(0), subthreshold(1), at or above threshold(2))

6(0), 8(1), 0(2)

15(0), 10(1), 0(2)

n.s (=0.4868) ^

  1. Values for continuous variables are shown as mean ± standard deviation, except age is shown as median ± standard deviation. # Welch’s two-sided t-test; ^ Chi-squared test; g: Hedges’ g-statistic effect size, n.s.: not significant.