Table 2 Top ROIs accounting for ~50% of the consistently highly-weighted connections (by FC edge count as well as by weight) in the classification model
From: Sparse machine learning of resting-state fMRI reveals brain-wide dysconnectivity in hyperacusis
ROI (1-414) | Part of network | Region | No. of highly-weighted FC edges | Co-ordinates [x, y, z] | Fraction of weight among consistently highly-weighted FC edges (%) | |
|---|---|---|---|---|---|---|
↑ trend in HA | ↓ trend in HA | |||||
69 | Dorsal Attention | Occipito-temporal/ fusiform | 0 | 67 | [-44, -42, -22] | 13.49 % |
201 | 2 | 44 | [34, -36, -24] | 8.952 % | ||
7 | Default mode | Parahippocampal cortex (PHC) | 14 | 0 | [-18, -38, -12] | 1.941 % |
106 | Control & Salience | Anterior & Dorsolateral Prefrontal cortex | 0 | 13 | [-28, 44, 30] | 1.794 % |
138 | 0 | 18 | [-28, 56, 12] | 2.931 % | ||
171 | 0 | 17 | [-28, 58, 0] | 3.002 % | ||
342 | 8 | 6 | [–6,42,50] | 2.509 % | ||
344 | 0 | 16 | [6,40,50] | 2.252 % | ||
82 | Dorsal Attention | Superior parietal lobule (SPL) | 18 | 0 | [-28, -62, 62] | 2.089 % |
277 | 0 | 12 | [18, -78, 50] | 1.255 % | ||
319 | Limbic | Orbitofrontal (OFC) | 1 | 13 | [–20,14,24] | 2.548 % |
Inferior temporal gyrus (ITG), Temporal poles | ||||||
123 | 1 | 11 | [-40, -22, -26] | 1.919 % | ||
326 | 0 | 14 | [48, -6, -40] | 2.347 % | ||
330 | 11 | 1 | [50, -28, -26] | 2.405 % | ||
411 | Subcortex | Globus Pallidus, Nucleus Accumbens | 16 | 3 | [20, -4, -1] | 3.05 % |
414 | 8 | 5 | [–6,8,11] | 1.931 % | ||