Extended Data Fig. 1: Biogenesis of proferrorosamine A. | Nature Synthesis

Extended Data Fig. 1: Biogenesis of proferrorosamine A.

From: Analysis of siderochelin biosynthesis reveals that a type II polyketide synthase catalyses diketide formation

Extended Data Fig. 1

(a) Comparation of the biosynthetic gene clusters of PFR-A and SIDs. (b) Proposed biosynthetic pathway of PFR-A29. The atom origins of the pyrroline unit (ring A) and associated precursors are indicated by different colours. PFR-A, proferrorosamine A; SID, siderochelin; AT, acyltransferase; KS, ketosynthase; CLF, chain length factor; ACP, acyl carrier protein; PKS, polyketide synthase; CoA, coenzyme A; PA, picolinic acid; PLP, pyridoxal phosphate; and ID, identity.

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