Fig. 6: Synthesis of orphenadrine using mechanochemically generated phenylsodium.
From: Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides

Isolated yields are reported as percentages. TMPH, 2,2,6,6-tetramethylpiperidine; THF, tetrahydrofuran; r.t., room temperature. See Supplementary Section 6 for full details.