Extended Data Fig. 6: Gene expression changes in SMC-derived cells after 12 weeks of plaque regression. | Nature Cardiovascular Research

Extended Data Fig. 6: Gene expression changes in SMC-derived cells after 12 weeks of plaque regression.

From: Cholesterol lowering depletes atherosclerotic lesions of smooth muscle cell-derived fibromyocytes and chondromyocytes

Extended Data Fig. 6

Differentially expressed genes (DEGs) were analyzed in SMC-derived cell clusters (C0-C4). Volcano plots show DEGs in each cluster. The top 10 downregulated and upregulated genes upon 12 weeks of ApoB-LP lowering are shown in cyan and ochre, respectively. Analysis was performed using the MAST method in Seurat with P values adjusted for multiple testing by the Bonferroni method.

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