Extended Data Fig. 8: Expression of genes encoding the TNF and IL1β receptors in SMC-derived cells. | Nature Cardiovascular Research

Extended Data Fig. 8: Expression of genes encoding the TNF and IL1β receptors in SMC-derived cells.

From: Cholesterol lowering depletes atherosclerotic lesions of smooth muscle cell-derived fibromyocytes and chondromyocytes

Extended Data Fig. 8

a-b, Expression of, encoding the TNF receptor 1, and Il1r1, encoding the IL1β receptor, in clusters C0-C4 in the 4-week (a) and 12-week (b) regression experiments. Tnfrsf1a and Il1r1 are expressed in SMC-derived cells with the highest expression in fibromyocytes and chondromyocytes. There is a trend towards lower expression of Tnfrsf1a after ApoB-LP lowering, which, however, did not reach genome-wide significance.

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