Extended Data Fig. 7: Characterization of anti-inflammatory program in murine atherosclerotic plaque immune cells that results from lipid-lowering treatment.
From: Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors
a–c, Canonical pathway analyses of differentially expressed transcripts in, respectively, myeloid, CD8+ T cells, or CD4+ T cells in lipid-lowered vs. untreated (control) mice. p value < 0.05 and |z-score| > 2. Some GO terms were edited for brevity. d–f, Heatmaps showing normalized transcript abundances of genes contributing to the respective GO terms for, respectively, myeloid, CD8+ T cells, or CD4+ T cells in lipid-lowered (light blue) vs. untreated (control; gray) mice. z-score shows scaled average expression.
