Extended Data Fig. 1: Proportions and corresponding gene expression patterns of human atherosclerotic plaque immune cell subclusters by single-cell RNA sequencing.
From: Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors
a–g, Proportions of CD8+ T cell (a), CD4+ T cell (b), Mixed (CD8+ or CD4+) and γδ T (Tγδ) cell (c), double-positive (DP; CD8+ CD4+) T cell (d), B cell (e), myeloid (f), and natural killer (NK) cell and innate lymphoid cell (ILC) (g) subclusters (left) and dot plots showing scaled average expression of corresponding markers (right). EM: effector memory; EMRA: terminally differentiated effector memory re-expressing CD45RA; CM: central memory; RM: resident memory; CTL: cytotoxic T lymphocyte; Reg: regulatory; MAIT: mucosal-associated invariant; NKT: natural killer T cell; Mono: monocyte; Mφ: macrophage; DC: dendritic cell. NE: normalized expression.
