Extended Data Fig. 8: Silencing of NF110 inhibits the improvement of CRAPIR on heart function after MI. | Nature Cardiovascular Research

Extended Data Fig. 8: Silencing of NF110 inhibits the improvement of CRAPIR on heart function after MI.

From: The highly conserved PIWI-interacting RNA CRAPIR antagonizes PA2G4-mediated NF110–NF45 disassembly to promote heart regeneration in mice

Extended Data Fig. 8

a, The heart contractile function was analyzed using Echocardiographic analysis (n=6 mice). b, The quantification of the percentage of pH3+ and Ki67+ cardiomyocytes (n=3 mice). c, The expression of cell cycle genes (n=4 biological replicates). Data are presented as mean ± s.e.m. Statistical analyses were performed by one-way ANOVA followed by Tukey’s Multiple Comparison tests (a-c). NC siRNA, negative control for siRNA; ago-CRAPIR, CRAPIR agomir; ago-NC, negative control for agomir; MI, myocardial infarction.

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