Extended Data Fig. 6: Action Potential after 4-aminopyridine (4-AP) and atropine (Atrop) perfusion.
a, Graphical scheme of action potential recording after 15 min of 4-AP 2.5 mM perfusion. b, Representative traces of AP from saline and IL-1β groups perfused with Tyrode solution or 4-AP. c, Action potential duration (APD) at 30%, 50%, 70% and 90% of repolarization, from saline and IL-1β groups during perfusion with Tyrode (Tyr) or 4-AP. Data are presented as individual values before and after condition. d, Graphical scheme of action potential recording after 15 min of Atropine 10 µM perfusion. e, Representative traces of AP from saline and IL-1β groups perfused with Tyrode solution or atropine. f, APD at 30%, 50%, 70% and 90% of repolarization, from saline and IL-1β groups during perfusion with Tyrode (Tyr) or atropine (Atrop). Data are presented as individual values before and after condition. P values in c and f were calculated with paired samples Student’s t-test (two-tailed).
