Extended Data Fig. 1: Comparative mRNA expression in atrial samples of mice injected with saline or IL1β for 15 consecutives days. | Nature Cardiovascular Research

Extended Data Fig. 1: Comparative mRNA expression in atrial samples of mice injected with saline or IL1β for 15 consecutives days.

From: IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression

Extended Data Fig. 1

a. Fold change was calculated dividing mean TPM values of IL1β -treated by the control group. Genes from the list of interest (n = 72) with absolute log2-fold change higher than 0.5 were displayed in red. The cumulative expression level of the genes is depicted in the x-axis as the sum of all the transcript per million of the four samples. b. Gene-set enrichment analysis interrogating KEGG data base. c. Gene-set enrichment analysis interrogating Reactome data base. d. Gene-set enrichment analysis interrogating Wikipathways data base. The top 10 up-regulated pathways are shown in blue and the top 10 down-regulated in orange (b-d).

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