Extended Data Fig. 10: Gene Ontology analysis of endothelial maturation within the mouse brain.

The differentially expressed gene signatures from the single cell endothelial subtypes of the developing and adult mouse brain that were used for pseudotime analysis by Moncole3 were processed for Gene Ontology analysis. The heatmap reflects which pathways and processes are upregulated in each of the unique endothelial cell subtypes (values represent the -log10 of the p-value). Colored by significance of pathway enrichment (2-sided p-value).