Extended Data Fig. 2: Generation of cardiac fibroblast-specific MYC overexpression mice.
Related to Fig. 2. a: Bar plots illustrating left ventricle chamber size and wall thickness by echocardiography in control and OE mice pre- and post-pressure overload (TAC0w, n = 6 [control] and 5 [OE]; TAC2w, 5 and 5; TAC4w, 6 and 5; TAC8w, 5 and 5; TAC12w, 4 and 5). Tcf21 iCre-R26StopFLMYC mice were used as controls. b: Kaplan–Meier survival curves for control and OE mice after TAC were compared using the Gehan-Breslow-Wilcoxon test (n = 10 [control] and 20 [OE]).
