Extended Data Table 5 DNN performance by demographic strata in the UCSF test dataset

From: Multiview deep learning improves detection of major cardiac conditions from echocardiography

Left/Right Ventricular Abnormality

(value (95%CI))

AUC

Sensitivity

Specificity

F1

Males

(N=3002)

0.904 (0.894–0.914)

0.826 (0.805–0.847)

0.81 (0.796–0.824)

0.725 (0.707–0.744)

Females

(N=3241)

0.907 (0.894–0.918)

0.79 (0.761–0.817)

0.864 (0.853–0.875)

0.655 (0.632–0.678)

Age 18–60

(N=2550)

0.912 (0.900–0.922)

0.834 (0.811–0.861)

0.84 (0.826–0.854)

0.723 (0.701–0.745)

Age 61-

(N=3695)

0.905 (0.895–0.915)

0.795 (0.773–0.818)

0.84 (0.828–0.851)

0.676 (0.655–0.695)

Diastolic Dysfunction

(value (95%CI))

AUC

Sensitivity

Specificity

F1

Males

(N=1069)

0.819 (0.795–0.843)

0.718 (0.692–0.745)

0.758 (0.719–0.799)

0.790 (0.769–0.809)

Females

(N=1145)

0.851 (0.832–0.872)

0.755 (0.729–0.780)

0.787 (0.750–0.820)

0.812 (0.793–0.830)

Age 18–60

(N=721)

0.830 (0.805–0.854)

0.543 (0.490–0.592)

0.876 (0.851–0.901)

0.624 (0.579–0.665)

Age 61-

(N=1493)

0.752 (0.726–0.780)

0.779 (0.760–0.797)

0.589 (0.540–0.644)

0.838 (0.824–0.851)

Valve Regurgitation

(value (95%CI))

AUC

Sensitivity

Specificity

F1

Males

(N=2088)

0.903 (0.887–0.919)

0.849 (0.815–0.885)

0.821 (0.806–0.835)

0.564 (0.532–0.598)

Females

(N=2060)

0.903 (0.886–0.918)

0.795 (0.748–0.839)

0.837 (0.822–0.850)

0.498 (0.454–0.535)

Age 18–60

(N=1715)

0.926 (0.911–0.941)

0.808 (0.756–0.857)

0.879 (0.865–0.893)

0.552 (0.506–0.598)

Age 61-

(N=2433)

0.888 (0.872–0.903)

0.835 (0.799–0.869)

0.792 (0.777–0.807)

0.526 (0.493–0.557)

  1. (DNN) Deep Neural Network, (LV) Left ventricle, (RV) Right ventricle, (AUC) Area under the receiver operating characteristic curve, (CI) Confidence Interval. All values are point estimate (95% confidence interval, derived via bootstrap).